What is the primary use of Sumatriptan (Imitrex)?

Sumatriptan, marketed as Imitrex, is primarily indicated for the treatment of acute migraine attacks. It belongs to a class of medications known as triptans, which function by acting as agonists at serotonin receptors, particularly the 5-HT_1B and 5-HT_1D receptor subtypes. This mechanism helps to alleviate migraine symptoms by constricting dilated intracranial blood vessels and inhibiting the release of pro-inflammatory neuropeptides.

While some individuals may use Sumatriptan for secondary headaches, such as tension-type headaches, its specific therapeutic design and clinical evidence predominantly support its use in managing migraines. This particular focus on acute migraine relief distinguishes it from medications aimed solely at preventing headaches or alleviating sinus pressure, which are typically addressed with different types of treatments.